What is the action of oral glucose after absorption?

• A. It increases circulating blood glucose levels after absorption in the GI tract
• B. It decreases circulating glucose levels
• C. It inhibits insulin release
• D. It blocks glucose uptake in muscle tissue

Answer: (B)

Glucose absorbed from the gut raises plasma glucose levels. This rise triggers insulin release from the pancreas, and insulin then promotes glucose uptake into liver, muscle, and adipose tissue, with storage as glycogen and continued utilization. It also suppresses hepatic glucose production. So the immediate action of oral glucose after absorption is an increase in circulating glucose, supported by insulin-mediated uptake and storage.