Which of the following is a contraindication to aspirin use?

• A. Active GI bleeding
• B. Mild constipation
• C. Allergic rhinitis
• D. Fever

Answer: (A)

Aspirin works by inhibiting platelets, which reduces clot formation and can worsen any ongoing bleeding. Therefore active GI bleeding is a clear contraindication because giving aspirin would raise the risk of continuing or worsening the hemorrhage.

Mild constipation does not affect platelet function or bleeding risk, so it isn’t a contraindication. Allergic rhinitis alone doesn’t automatically prohibit aspirin use, though NSAID-exacerbated respiratory disease is a consideration in some patients with asthma and nasal polyps. Fever isn’t a contraindication either; aspirin can be used as an antipyretic, though other factors (like age and viral illness risks) may influence its use in certain groups.