Which route is typically used for administering oral glucose in acute hypoglycemia?

• A. Inhalation
• B. Intravenous
• C. Subcutaneous
• D. By mouth

Answer: (D)

When a patient presents with acute hypoglycemia and is able to swallow, the standard approach is to give glucose by mouth. This works because oral glucose (in tablets or gel) is rapidly absorbed through the gastrointestinal tract, raising blood glucose quickly without needing IV access. It’s practical, easy to administer, and effective for a conscious patient who can protect their airway.

If the patient cannot swallow or is unconscious, the oral route isn’t safe or feasible, and alternative routes are used: intravenous glucose provides the fastest, most reliable correction, and glucagon given intramuscularly or subcutaneously is useful when IV access isn’t available.

Inhaled glucose products exist but are not the typical option in most emergency settings due to variability in absorption and technique, so by mouth remains the preferred route for a conscious patient.