Which routes are acceptable for acetaminophen administration in adults and children?

• A. PO or PR
• B. IV only
• C. IM only
• D. Subcutaneous

Answer: (A)

Acetaminophen can be given safely by enteral routes for both adults and children. Oral administration is preferred when the patient can take medicine by mouth, offering reliable absorption and straightforward dosing. Rectal administration provides a workable alternative when swallowing isn’t possible or when vomiting is present, making it useful in children and others who can’t take pills or liquids by mouth. While intravenous acetaminophen is used in some hospital settings for rapid effect or when enteral routes aren’t feasible, that option isn’t reflected in this question’s set. Intramuscular and subcutaneous routes are not standard for acetaminophen. Therefore, the acceptable routes in this context are the oral and rectal options.